· KPTIQ

Karyopharm Therapeutics Inc.

Closing price No closing price on file for KPTIQ from our free price source.

Latest quarter · ended Jun 30, 2026

Sales slipped and cash got weaker

descriptionFiled Aug 13, 2026
Revenue growthShrinking
−11.9%
Quarter ended Sep 30, 2024: +7.7% sales vs. a year beforeQuarter ended Dec 31, 2024: −9.5% sales vs. a year beforeQuarter ended Mar 31, 2025: −9.4% sales vs. a year beforeQuarter ended Jun 30, 2025: −11.4% sales vs. a year beforeQuarter ended Sep 30, 2025: +13.6% sales vs. a year beforeQuarter ended Dec 31, 2025: +11.6% sales vs. a year beforeQuarter ended Mar 31, 2026: +16.8% sales vs. a year beforeQuarter ended Jun 30, 2026: −11.9% sales vs. a year before
Sep '24Jun '26
$33.4M vs. $37.9M a year ago
Cash from operationsWorse
−$24.9M
Quarter ended Sep 30, 2024: −$19.5M cash from operationsQuarter ended Dec 31, 2024: −$25.8M cash from operationsQuarter ended Mar 31, 2025: −$39M cash from operationsQuarter ended Jun 30, 2025: −$18.7M cash from operationsQuarter ended Sep 30, 2025: −$5.86M cash from operationsQuarter ended Dec 31, 2025: −$11.8M cash from operationsQuarter ended Mar 31, 2026: −$22.7M cash from operationsQuarter ended Jun 30, 2026: −$24.9M cash from operations
Sep '24Jun '26
vs. −$18.7M a year ago
Share countDiluting
+161.6%
Quarter ended Sep 30, 2024: 125.31M sharesQuarter ended Dec 31, 2024: 126.24M sharesQuarter ended Mar 31, 2025: 8.64M sharesQuarter ended Jun 30, 2025: 8.67M sharesQuarter ended Sep 30, 2025: 17050.88M sharesQuarter ended Dec 31, 2025: 18.34M sharesQuarter ended Mar 31, 2026: 22.66M sharesQuarter ended Jun 30, 2026: 22.68M shares
Sep '24Jun '26
22.68M shares vs. 8.67M a year ago

Numbers come from the company's own 10-Q and 10-K reports filed with the SEC. Each bar is one quarter, oldest on the left. The colored bar is the latest. Hover over or tap a bar to see its number.

Smart money pulse

What insiders and funds are doing

Mixed Insiders: as of Nov 13 Funds: as of Jun 30, 2026
−1000+100 −30
  • account_balance
    7 funds bought, 3 sold in the quarter ended Jun 30, 2026, counting funds that hold 500 stocks or fewer and $1M+ of this one. Index funds and banks are left out.
  • info
    21 real insider sales in 12 months. $351K in total, not counting planned sales.

−100 means everyone selling, +100 everyone buying. This is data, not advice.

How the Pulse works

Pulse runs from −100 (everyone selling) to +100 (everyone buying). Half comes from insiders: real buyers vs. real sellers in the last 90 days (Form 4). Half comes from funds: funds that bought vs. funds that sold last quarter (13F). 13F is a snapshot of long positions on the last day of the quarter, filed up to 45 days later. It does not show short positions or trades since then.

Who owns it

98 funds report owning KPTIQ or KPTI, up from 75

Holdings as of Jun 30, 2026
New37
Added29
Held19
Trimmed13
Sold out14

Last quarter

Who bought and who sold

Apr–Jun 2026
Acorn Capital Advisors, LLC
+427%
Commodore Capital LP
Sold
Catalio Capital Management, LP
+5%
Avidity Partners Management LP
+99%
Kalehua Capital Management LLC
New
NEA Management Company, LLC
New
Ghisallo Capital Management LLC
New
Ikarian Capital, LLC
Sold

Change in shares held from Mar 31 to Jun 30, 2026, biggest holdings first. Only funds that hold 500 stocks or fewer and $1M+ of this one: index funds and banks own almost everything, so their changes say little. Bars stop at ±100%.

Insider trades · last 12 months

Real buys and sales

● Open-market buy● Open-market sale
CEOCFOOther officersDirectorsDecJanFebMarAprMayJunJulAugSepOctNovStock grant · Jan 27 · 92 shStock grant · Jan 31 · 129,660 sh · 4 peopleStock grant · Jan 31 · 32,415 shStock grant · Feb 5 · 81,060 shStock grant · May 13 · 3,611 sh · 5 peopleStock grant · May 13 · 4,920 shStock grant · May 21 · 93,048 sh · 6 peopleOpen-market sale · Jan 21 · $1.58KOpen-market sale · Jan 28 · $352Open-market sale · Feb 3 · $10.2KOpen-market sale · Feb 17 · $3.26KOpen-market sale · Mar 2 · $177K · 5 peopleOpen-market sale · Mar 2 · $116KOpen-market sale · Apr 21 · $4.01KOpen-market sale · May 14 · $13.8K · 5 peopleOpen-market sale · May 14 · $20.9KOpen-market sale · Jul 28 · $1.34KOpen-market sale · Sep 1 · $38Open-market sale · Oct 1 · $450Open-market sale · Oct 16 · $1.65K
CEOCFOOther officersDirectorsJunJulAugSepOctNovOpen-market sale · Jul 28 · $1.34KOpen-market sale · Sep 1 · $38Open-market sale · Oct 1 · $450Open-market sale · Oct 16 · $1.65K

Last 6 months. A wider screen shows 12.

Showing 21 real trades. Hidden: 19 stock grants. Those happen on a schedule and say little about what an insider thinks. Bigger dot means a bigger trade.

Real trades, newest first

Oct 16 Kristin Abate Chief Accounting Officer Open-market sale $1.65K 4,788 sh at $0.34 Sold 20% of stake
Oct 1 Kristin Abate Chief Accounting Officer Open-market sale $450 378 sh at $1.19 Sold 2% of stake
Sep 1 Kristin Abate Chief Accounting Officer Open-market sale $38 19 sh at $2.02 Sold 1% of stake
Jul 28 Stuart Poulton EVP, Chief Development Officer Open-market sale $1.34K 189 sh at $7.10 Sold 1% of stake
May 14 Richard Paulson President and CEO, Director Open-market sale $20.9K 2,203 sh at $9.50 Sold 1% of stake
May 14 Reshma Rangwala EVP & Chief Medical Officer Open-market sale $3.88K 408 sh at $9.50 Sold 1% of stake
May 14 Stuart Poulton EVP, Chief Development Officer Open-market sale $3.83K 403 sh at $9.50 Sold 1% of stake
May 14 Sohanya Cheng EVP & Chief Commercial Officer Open-market sale $3.08K 324 sh at $9.50 Sold 1% of stake
May 14 Michael Mano EVP, CLO&Secretary Open-market sale $2.53K 266 sh at $9.50 Sold 1% of stake
May 14 Kristin Abate Chief Accounting Officer Open-market sale $504 53 sh at $9.50 Sold 1% of stake
Show 11 older real trades
Apr 21 Reshma Rangwala EVP & Chief Medical Officer Open-market sale $4.01K 449 sh at $8.94 Sold 1% of stake
Mar 2 Richard Paulson President and CEO, Director Open-market sale $116K 12,361 sh at $9.41 Sold 4% of stake
Mar 2 Stuart Poulton EVP, Chief Development Officer Open-market sale $48K 5,101 sh at $9.41 Sold 5% of stake
Mar 2 Reshma Rangwala EVP & Chief Medical Officer Open-market sale $47.7K 5,066 sh at $9.41 Sold 8% of stake
Mar 2 Sohanya Cheng EVP & Chief Commercial Officer Open-market sale $43.3K 4,604 sh at $9.41 Sold 4% of stake
Mar 2 Michael Mano EVP, CLO&Secretary Open-market sale $33.2K 3,526 sh at $9.41 Sold 4% of stake
Mar 2 Kristin Abate Chief Accounting Officer Open-market sale $5.26K 559 sh at $9.41 Sold 2% of stake
Feb 17 Stuart Poulton EVP, Chief Development Officer Open-market sale $3.26K 378 sh at $8.63 Sold 1% of stake
Feb 3 Lori Macomber EVP, CFO & Treasurer Open-market sale $10.2K 1,626 sh at $6.30 Sold 2% of stake
Jan 28 Kristin Abate Chief Accounting Officer Open-market sale $352 50 sh at $7.03 Sold 1% of stake
Jan 21 Kristin Abate Chief Accounting Officer Open-market sale $1.58K 265 sh at $5.96 Sold 1% of stake

Showing every filing. Dashed circles are routine: grants, tax withholding, option exercises and planned sales.

Big bets

Funds with a big share of their money in KPTIQ or KPTI

As of Jun 30, 2026
FundOf fundOwnsValueChange
Acorn Capital Advisors, LLC4%6.7%$14.8M+427%
Kalehua Capital Management LLC5%3.0%$6.7MNew

Funds that hold 150 stocks or fewer, where this stock is 3% or more of what they reported. "Of fund" is its share of the fund's 13F value.

"Owns" is shares reported divided by shares outstanding.

Where this data comes from. Insider trades, fund holdings, activist stakes and company results come from public SEC EDGAR filings (Forms 4, 13F, 13D/13G, 10-Q and 8-K). Congress trades come from the STOCK Act reports members file with the House Clerk and the Senate. Daily closing prices come from post-no-preference/stocks on DoltHub, a community-run database shared under CC BY-SA 4.0; the prices we show stay under that license. They are each day's close, not live or official exchange prices.

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